SMIM1: Small integral membrane protein 1 (Vel blood group) SMIM11A: Small integral membrane protein 11A: SMIM10: Small integral membrane protein 10: SMIM10L1: Small integral membrane protein 10 like 1: SMIM10L2A: Small integral membrane protein 10 like 2A: SMIM10L2B: Small integral membrane protein 10 like 2B:

smim1_mouse

This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries.

However, the exact nature of the Vel antigen and how it is presented by SMIM1 are poorly understood. Smim1 - Small integral membrane protein 1 - Mus musculus (Mouse) - Smim1 gene & protein UniProtKB - P0C8K7 (SMIM1_MOUSE) Identifying SMIM1, SMall Integral Membrane protein 1, as the protein encoding the Vel antigen has significantly improved the identification of Vel negative donors. These rare donors are essential for safe blood transfusions. The Vel blood group is associated with the SMIM1 gene, which is located in the 1p36 region of chromosome 1. This gene produces small integral membrane protein 1, a single-pass transmembrane protein which carries the Vel antigen but whose structure and function are otherwise poorly understood. SMIM1 was tagged with an opsin-derived N-glycosylation reporter at either the N- or C-terminus and synthesized in vitro using rabbit reticulocyte lysate supplemented with canine pancreatic microsomes as a source of ER membrane. SMIM1 topology was then determined by assessing the N-glycosylation of its N- or C-terminal tags.

Las personas con esta sangre tienen una mutación en su 18 Mar 2013 from the University of Vermont and France has found the missing molecule—a tiny protein called SMIM1—and the mystery is solved. 8 Apr 2013 The researchers discovered that the presence of the Vel antigen on our red blood cells is controlled by a previously unknown protein (SMIM1) STX5 - Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion Download scientific diagram | SMIM1 protein. a. The schematic of the SMIM1 protein with I-TASSER predicted 3D-structure showing the extracellular domain SMIM1. B3GALT4.

Unit … SMIM1 gene products (22): Antibodies (1), Custom CRISPR Plasmid (1), Proteins (1), SYBR Green Primers (2), , shRNA Products (6), siRNA Products (11) Peer-Reviewed Papers. Related Gene Products. SMIM1 - Explore an overview of SMIM1, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.

SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system. Research output: Contribution to journal › Article

This antibody reacts with Human, Mouse samples. Supplied as 150 µL purified antibody (0.43 mg/mL).

Gene information about ENSG00000235169 / SMIM1 - small integral membrane protein 1 (Vel blood group)

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Diseases associated with SMIM1 include Blood Group, Vel System and Melnick-Needles Syndrome .
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The Vel negative phenotype is caused by a homozygous 17 base pair deletion in exon 3 of the SMIM1 gene which 034, VEL, Vel, SMIM1, protein, v1.0 (160620). 035, CD59, CD59, CD59, protein, v2.0 01-MAR-2020. 036, AUG, Augustine, SLC29A1, protein, 8th April 2019. 2017年12月10日根据Vel－产生的分子机制分别设计可特异扩增野生型和缺失突变SMIM1序列的引物，采用序列特异性引物PCR检测样本的基因型，通过DNA测序 2 Mar 2021 Smim1: 0.5. 0.6.

Each vial contains slightly different sequences t smim1 ID ZDB-GENE-081022-87 Name small integral membrane protein 1 Symbol smim1 Nomenclature History Previous Names. si:dkey-23c22.1; zgc:194254; Type protein_coding_gene Location Chr: 8 Mapping Details/Browsers Description Involved in nucleate erythrocyte development.
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SMIM1 encodes a 78-amino acid, single transmembrane domain (TMD) containing protein with a predicted TMD at amino acids 47 to 67. The protein was previously predicted to be a type I transmembrane protein (Storry et al., 2013) but has recently been shown to be a type II transmembrane domain protein with amino acids at positions 1 to 47 predicted to constitute the cytoplasmic domain while

0.4. 0.6. 0.8. 1 un sp lice d. Smim1 data model. 95% c.i.. 0.5.